DPCstruct | MC40477

Metacluster Properties and Pfam Annotations

Number of structural domains624
Mean domain length (aa)75 ± 11 aa
Standard deviation of domain lengths11.48
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.82
Pfam Score99.41
Assigned Pfam label(s) CL0220- CL0022

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4V5D8 333-402 None
W4V6A2 93-166 None
W4V9J4 193-266 None
A0A7X9KXE4 1056-1129 None
W4V9Y4 127-195 None
W4VAI7 368-431 None
W4VAK1 496-560 None
W4VDH4 79-150 None
A0A645I5P5 1-74 None
A0A1K1LNZ5 888-963 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.