DPCstruct | MC40443

Metacluster Properties and Pfam Annotations

Number of structural domains652
Mean domain length (aa)205 ± 52 aa
Standard deviation of domain lengths51.81
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.85
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)11.17
Pfam Score76.48
Assigned Pfam label(s) CL0023- PF16322- CL0063- CL0395- PF20236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y9Z8Y7 370-660 None
A0A6C0GGR2 215-372 None
A0A835U7F8 27-194 None
M7BP62 130-441 None
A0A180GAJ9 22-179 None
H3DWB0 414-602 None
H3E1G0 313-531 None
A0A2U1Q1J5 40-219 None
A0A369GQM8 4-177 None
A0A7Y9J7D5 70-256 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.