DPCstruct | MC40443

Metacluster Properties and Pfam Annotations

Number of structural domains652
Mean domain length (aa)205 ± 52 aa
Standard deviation of domain lengths51.81
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.85
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)11.17
Pfam Score76.48
Assigned Pfam label(s) CL0023- PF16322- CL0063- CL0395- PF20236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C1HJL5 20-193 None
A0A1L7XF71 63-386 None
A0A7C2KG34 25-197 None
A0A1J5F7W0 20-144 None
A0A2J6QLC6 94-382 None
A0A426YR61 4-242 None
I7MGW3 7-276 None
A0A498MD98 334-600 None
B7FZN7 139-321 None
B7G6S0 98-308 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.