DPCstruct | MC40443

Metacluster Properties and Pfam Annotations

Number of structural domains652
Mean domain length (aa)205 ± 52 aa
Standard deviation of domain lengths51.81
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.85
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)11.17
Pfam Score76.48
Assigned Pfam label(s) CL0023- PF16322- CL0063- CL0395- PF20236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H0A9C0 87-291 TGKRNNSQRPSNNSKEIVPGVDLSDNQYTLKQRLLFNRYKLYDQDGGLVMKAKQKILKMKEDFRFKNSDDEEVMHVKAENIMDVAGD…
A0A2S0L0M1 114-264 ITFYYDAAGYLTGSAAETDGAVVRRNAAGTVIGTELIEGGKTLYYDGSGNLTGARVVSGGTALVYNAAGEVYSREVTTGELTTYYNA…
A0A1E7FSM0 36-222 None
A0A0S6X9K4 33-257 None
A0A369JU63 21-282 None
A0A1Y1V1G6 11-188 None
A0A0C9ME37 3-154 None
A0A0S6X8K6 13-171 None
G0RRD3 28-262 None
M9LIX7 103-408 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.