DPCstruct | MC40443

Metacluster Properties and Pfam Annotations

Number of structural domains652
Mean domain length (aa)205 ± 52 aa
Standard deviation of domain lengths51.81
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score75.85
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)11.17
Pfam Score76.48
Assigned Pfam label(s) CL0023- PF16322- CL0063- CL0395- PF20236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D3GNV6 36-234 None
M1A1W1 1-132 None
A0A285CLF0 61-233 None
A0A0V0QTC0 21-273 None
A0A1U7W9D0 1-203 None
Q5ARH0 3-224 None
A0A3B6N0E0 3-146 None
A0A4P6YGQ3 10-131 None
A0A812NM92 124-353 None
H2AXM1 8-229 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.