DPCstruct | MC39405

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)167 ± 34 aa
Standard deviation of domain lengths34.44
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.38
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.56
Pfam Score92.52
Assigned Pfam label(s) CL0023- CL0125- PF01576- CL0072- PF00773

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
V4ADC5 1-165 None
M7CF36 90-249 None
M7BWB2 42-231 None
A0A175W8F9 77-278 None
A0A1X7SSX3 11-109 None
A0A818G1K8 724-879 None
B0W191 347-474 None
A0A5D6XX74 609-817 None
C3YJB8 32-220 None
A0A0M0JVM3 1-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.