DPCstruct | MC39405

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)167 ± 34 aa
Standard deviation of domain lengths34.44
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.38
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.56
Pfam Score92.52
Assigned Pfam label(s) CL0023- CL0125- PF01576- CL0072- PF00773

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9E365 51-189 None
U4UIY1 179-326 None
A0A3B5B9U9 31-203 None
A0A5A8D162 36-218 None
A0A6J2K0Y0 2-142 None
L2GK99 2-139 None
Q8SS35 1-195 None
A0A2U1Q3L3 52-241 None
A0A484CEI1 2-105 None
A0A2G9S1H8 2-129 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.