DPCstruct | MC37540

Metacluster Properties and Pfam Annotations

Number of structural domains433
Mean domain length (aa)160 ± 30 aa
Standard deviation of domain lengths30.28
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.62
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)21.72
Pfam Score99.45
Assigned Pfam label(s) CL0023- PF08719- CL0387

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F1L1H5 15-189 None
W9Y027 313-430 None
A0A015MUW8 216-376 None
M2MZ96 22-218 None
H2L297 16-300 None
A0A0N5ALJ1 136-265 None
A0A2S7PZ69 46-219 None
A0A2E3LZE6 211-378 None
A0A7S4Q638 103-291 None
U9U7K9 451-613 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.