DPCstruct | MC37540

Metacluster Properties and Pfam Annotations

Number of structural domains433
Mean domain length (aa)160 ± 30 aa
Standard deviation of domain lengths30.28
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.62
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)21.72
Pfam Score99.45
Assigned Pfam label(s) CL0023- PF08719- CL0387

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1X2GC42 5-160 YFWGHSKTSEYACFSQWYGSAFKDKEGHTYANAEQYMMYQKAALMGDAVMGTAILAGKNPKAIKAMGRKIKNFDEALWNKHKETIVF…
A0A1G6Q9K0 7-163 MTLFFSKEDALSNWHPSNFVVKGVEFNCVEQFMMYCKAKLFSDQVVADLVLKAQHPKDQKALGRRVANYDDRVWSQRREGIVRHGAY…
G4TCM7 742-987 None
Q5B078 471-731 None
A0A7S0ATR8 162-334 None
A0A7S4R150 39-187 None
S7Q215 93-251 None
A0A0K0EFT9 271-491 None
A0A1I8I5I5 6-157 None
A0A3S2PWB7 48-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.