DPCstruct | MC3666

Metacluster Properties and Pfam Annotations

Number of structural domains98
Mean domain length (aa)94 ± 17 aa
Standard deviation of domain lengths16.81
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.12
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)37.37
Pfam Score99.32
Assigned Pfam label(s) CL0229- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A4VDJ6 17-120 None
A0A5A8CZ89 2-103 None
A0A0D8Y6R3 508-612 None
C9S8K5 2-89 None
A0A397IID6 2-61 None
A0A0D9X1P1 21-120 None
A0A422Q8I4 6-101 None
A0A830CMG7 12-112 None
A0A4D8ZUF0 10-100 None
A0A812NGH3 1-90 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.