DPCstruct | MC35892

Metacluster Properties and Pfam Annotations

Number of structural domains224
Mean domain length (aa)109 ± 19 aa
Standard deviation of domain lengths18.58
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.66
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)16.74
Pfam Score85.51
Assigned Pfam label(s) CL0154- CL0548- CL0522

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L7LZB3 324-471 None
A0A2R6T7X8 75-185 None
A0A4R6LWZ0 1-111 None
A0A7Y0IHW9 45-157 None
A0A536X5G8 45-148 None
A0A1Y1X7J9 758-865 None
A0A0W0SDB2 27-125 None
A0A7S4W545 160-276 None
O96168 276-420 None
A0A853ITW6 93-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.