DPCstruct | MC35892

Metacluster Properties and Pfam Annotations

Number of structural domains224
Mean domain length (aa)109 ± 19 aa
Standard deviation of domain lengths18.58
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.66
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)16.74
Pfam Score85.51
Assigned Pfam label(s) CL0154- CL0548- CL0522

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q2CYH0 8-102 FVSFALPVSTTETLPGLEIDAVVGVVVGIATRPRDMAHNPEMGYVNTAARQDAIGAMVQQAQEAGAHAIIGVRFDGGKISETVTELT…
A0A023CUG0 1-80 MILGIVNATVKRTLTADRIDEVDQYDEMYNQVKEKLIERAAVKEGDGVIGVNFNSEIVRVAVGPKYMLLHGYGTAIKFPK
A0A7G9FCQ1 11-155 None
G0TKP2 111-210 None
A0A1I8IMS7 118-276 None
A0A7C3MTE0 28-113 None
A0A4W4G995 52-176 None
A0A1W1EG60 1-103 None
A0A368FCU2 85-188 None
A0A2T6D016 2-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.