DPCstruct | MC35708

Metacluster Properties and Pfam Annotations

Number of structural domains880
Mean domain length (aa)95 ± 19 aa
Standard deviation of domain lengths18.94
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.53
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)19.78
Pfam Score99.07
Assigned Pfam label(s) CL0221- CL0114- CL0539- CL0196- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S2L4Q8 332-472 None
A0A3Q0IUB9 222-307 None
A0A3Q0IZW8 216-328 None
A0A3Q0J2A3 38-134 None
A0A5P1F958 93-187 None
A0A5P1FIZ5 941-1039 None
A0A182U275 61-163 None
A0A135V9I2 510-599 None
S7Q237 1-83 None
S7QK69 1-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.