DPCstruct | MC35708

Metacluster Properties and Pfam Annotations

Number of structural domains880
Mean domain length (aa)95 ± 19 aa
Standard deviation of domain lengths18.94
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.53
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)19.78
Pfam Score99.07
Assigned Pfam label(s) CL0221- CL0114- CL0539- CL0196- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7IMW4 7-97 SCTESNFVEIIHNYCQKNNLCRPEFILVETSGPPHNRRFFSKLKIGTREYPVAEGKKIKEAEQKAAKLAWSALREQSDNDSKVSVGS…
A0A2P7P0M4 1-70 NPKSALQEWAQGQGRPLPTYRVADRTGSDHAPTFTVEVSVQDVQPLTAQGRSRQEAEKAAATALLKREGV
A0A3B6MZM9 1-101 None
A0A3B6NP58 1-108 None
A0A3B6PJ76 2-82 None
A0A1V5UX05 157-231 None
A0A287DA24 87-205 None
A0A4Y7L8A1 673-770 None
A0A1S3Q5H9 387-471 None
A0A4Y7JRR8 103-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.