DPCstruct | MC35708

Metacluster Properties and Pfam Annotations

Number of structural domains880
Mean domain length (aa)95 ± 19 aa
Standard deviation of domain lengths18.94
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.53
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)19.78
Pfam Score99.07
Assigned Pfam label(s) CL0221- CL0114- CL0539- CL0196- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2HUN2 4-107 None
A0A183P5H8 247-341 None
A0A891X744 154-226 None
A0A3B3VJL5 117-230 None
A0A3B3VPE0 197-345 None
A0A6V7UCP2 4-68 None
A0A2J8VRE6 12-90 None
A0A7N4NKQ5 392-512 None
A0A1S3MQ20 237-345 None
A0A4S4EUL0 29-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.