DPCstruct | MC35708

Metacluster Properties and Pfam Annotations

Number of structural domains880
Mean domain length (aa)95 ± 19 aa
Standard deviation of domain lengths18.94
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.53
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)19.78
Pfam Score99.07
Assigned Pfam label(s) CL0221- CL0114- CL0539- CL0196- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P8G6W2 2-175 None
A0A835PYS7 53-151 None
A0A445AVM6 287-382 None
A0A1S3E072 10-93 None
E9HQJ5 14-121 None
A0A158PJV0 100-195 None
Q0DJA3 36-133 None
A0A183B3L5 43-124 None
A0A3S4Q3Y7 1-121 None
A0A3S4Q7B3 2-94 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.