DPCstruct | MC35708

Metacluster Properties and Pfam Annotations

Number of structural domains880
Mean domain length (aa)95 ± 19 aa
Standard deviation of domain lengths18.94
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.53
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)19.78
Pfam Score99.07
Assigned Pfam label(s) CL0221- CL0114- CL0539- CL0196- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J5TG07 328-438 None
K3W6U0 85-177 None
A0A4S8MEA3 5-98 None
A0A4S8MTP7 5-91 None
A0A3N7GCN3 1-110 None
A0A2V1CYY9 68-166 None
A0A6V7PIB6 113-232 None
A0A821ULV9 51-150 None
A0A2K2DBT2 280-356 None
A0A5N5G7X6 207-295 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.