DPCstruct | MC35665

Metacluster Properties and Pfam Annotations

Number of structural domains736
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.23
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.23
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)17.76
Pfam Score96.59
Assigned Pfam label(s) PF07833- CL0020- CL0317- CL0105- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A137SX05 160-292 None
A0A844X9F8 403-540 None
A0A349G674 406-516 None
R6UBE5 144-266 None
A0A645F654 10-127 None
A0A1V6BP21 180-289 None
A0A7C2IQD2 88-251 None
V2YHL9 579-726 None
V2YGY8 13-169 None
A0A1E5LK54 164-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.