DPCstruct | MC35665

Metacluster Properties and Pfam Annotations

Number of structural domains736
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.23
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.23
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)17.76
Pfam Score96.59
Assigned Pfam label(s) PF07833- CL0020- CL0317- CL0105- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
N1ZL26 20-140 TMAFTVFAGSKISINDIMLCIETVAVDDVAMVSLRDIYECFGANITWQADTQEIVVVNTDKTIKFKVNSATATVNNVPVTLSHAVIQ…
A0A645CLT8 4-135 PNTSSVLINGKKVDFESYNIDGFNYFKLRDIALALKDTGKGFEVEWDGNKNSVSMKSYSSYTQVGGELSLPESYLNKQALVSTVLLY…
A0A3B0C4E6 6-186 None
A0A1E3C1K1 136-299 None
A0A7X9B9E9 779-897 None
A0A7X9GC16 2-92 None
A0A1V5XF81 18-143 None
A0A1V5XJ98 513-626 None
A0A1C6GIM4 517-656 None
A0A5C4SW88 81-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.