DPCstruct | MC35665

Metacluster Properties and Pfam Annotations

Number of structural domains736
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.23
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.23
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)17.76
Pfam Score96.59
Assigned Pfam label(s) PF07833- CL0020- CL0317- CL0105- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A373Q7Q2 524-643 None
A0A2S5H0W0 1-119 None
A0A379DAH6 643-778 None
A0A1Q8Z5Q0 587-672 None
R5E8Z6 40-203 None
A0A1J5C5E4 884-1002 None
A0A3A8YL82 20-178 None
E2ZA92 227-350 None
A0A1I4G9A4 44-193 None
A0A1I4RGD9 204-348 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.