DPCstruct | MC35665

Metacluster Properties and Pfam Annotations

Number of structural domains736
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.23
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.23
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)17.76
Pfam Score96.59
Assigned Pfam label(s) PF07833- CL0020- CL0317- CL0105- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E5L555 191-302 None
W8T3I5 509-642 None
A0A1Q5X975 2-132 None
L0DYI1 176-301 None
A0A1H6B829 71-237 None
A0A2N6L058 86-221 None
A0A356C8C3 1-91 None
A0A7V4B2P7 38-173 None
A0A1V2YEW1 185-323 None
A0A4Q9DKH1 350-478 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.