DPCstruct | MC35665

Metacluster Properties and Pfam Annotations

Number of structural domains736
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.23
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.23
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)17.76
Pfam Score96.59
Assigned Pfam label(s) PF07833- CL0020- CL0317- CL0105- CL0037

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B8K2B4 7-82 None
A0A7X3DJJ9 5-123 None
A0A7X7AWG2 241-345 None
A0A7X0RTD6 35-171 None
A0A7V6Q1G1 143-261 None
A0A2K9DZY2 19-145 None
A0A2K9E3B6 30-154 None
A0A2S8RCB7 25-153 None
A0A2S8RET2 168-289 None
A0A1Y4UCR3 3-98 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.