DPCstruct | MC35555

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)245 ± 45 aa
Standard deviation of domain lengths45.13
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score73.03
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.53
Pfam Score60.42
Assigned Pfam label(s) PF00253- PF07850- PF20520

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D8RMG8 20-262 TVSAHSSSAMAPAFIWSNLRCVDSGQQVNYQVSDARSVTRAALEQLDMKKCLDESEKPADLLVAFVGSEVRSVELSNELSSYTVEKL…
A0A553R9D1 12-216 SFCGCFAQVPLLMWTSYGSSMPHQAGPAAGHRVTGAELQAYLKSAFSTAPRNVLLFLQEKLSVDDFTMFAGVFGNKQDSVFLSVESA…
A0A2K5Y706 1-259 None
A0A7J7LYW6 7-268 None
A0A556TU15 14-239 None
A0A7N0RIZ5 23-322 None
A0A090LQ80 174-496 None
A0A059B1X8 1-289 None
A0A0S6XS14 16-261 None
A0A5B7FFY8 2-226 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.