DPCstruct | MC35555

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)245 ± 45 aa
Standard deviation of domain lengths45.13
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score73.03
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)13.53
Pfam Score60.42
Assigned Pfam label(s) PF00253- PF07850- PF20520

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V2LKT7 211-503 None
I1CES1 8-189 None
A0A0L8VQ32 2-237 None
A0A6S7IBB2 19-230 None
A0A6U2B0E9 1-279 None
A0A498MU45 433-614 None
A0A2U1PVQ1 16-359 None
I1C6F7 2-213 None
A0A0L0SZC3 4-255 None
A0A1Y2IKR5 93-359 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.