DPCstruct | MC35435

Metacluster Properties and Pfam Annotations

Number of structural domains592
Mean domain length (aa)65 ± 9 aa
Standard deviation of domain lengths8.83
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.12
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.13
Pfam Score97.23
Assigned Pfam label(s) PF00057- CL0123- PF00095- PF01826- CL0692

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5S6PIY2 7-73 None
A0A3Q3B5L9 97-161 None
H3C3T1 64-140 None
A0A674J6B1 97-183 None
A0A7I8VBR6 261-314 None
A0A210Q800 90-147 None
A0A2A2M1I6 53-115 None
A0A452GZ10 15-79 None
H2P238 2-49 None
A0A821NHC7 3-79 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.