DPCstruct | MC35435

Metacluster Properties and Pfam Annotations

Number of structural domains592
Mean domain length (aa)65 ± 9 aa
Standard deviation of domain lengths8.83
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.12
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.13
Pfam Score97.23
Assigned Pfam label(s) PF00057- CL0123- PF00095- PF01826- CL0692

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
P26228 3-56 None
A0A812AX16 109-184 None
H3E1U0 496-554 None
A0A5K3EM77 855-911 None
A0A670IG83 62-127 None
A0A3Q3LLB8 24-82 None
A0A183F3S9 40-115 None
A0A183FSR8 44-112 None
R4G7H0 63-125 None
A0A7R9E5G9 659-715 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.