DPCstruct | MC35372

Metacluster Properties and Pfam Annotations

Number of structural domains942
Mean domain length (aa)235 ± 48 aa
Standard deviation of domain lengths48.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.91
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.70
Pfam Score96.40
Assigned Pfam label(s) CL0126- CL0523- PF16491

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H6G618 40-377 None
G5IDW9 71-278 None
A0A0G0D5I3 20-253 None
A0A3D4MGL3 1-390 None
Q1ILN4 308-539 None
A0A7J6TIW7 275-541 None
A0A1Y4W7I8 141-352 None
A0A7J6Z2M3 276-526 None
U6RDX2 66-285 None
A0A812NGV3 473-715 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.