DPCstruct | MC35372

Metacluster Properties and Pfam Annotations

Number of structural domains942
Mean domain length (aa)235 ± 48 aa
Standard deviation of domain lengths48.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.91
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.70
Pfam Score96.40
Assigned Pfam label(s) CL0126- CL0523- PF16491

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B9FVY4 1-188 None
A0A4Q2BNJ2 110-361 None
A0A256KKD9 10-201 None
A0A7Y5FF91 16-291 None
A0A7W5TTG7 18-211 None
A0A183V7T6 11-262 None
A0A7J5AP33 30-408 None
A0A2E7CCP5 5-193 None
A0A2G8KMB5 99-395 None
L8LW01 245-553 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.