DPCstruct | MC33911

Metacluster Properties and Pfam Annotations

Number of structural domains718
Mean domain length (aa)160 ± 26 aa
Standard deviation of domain lengths25.94
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.47
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)14.43
Pfam Score96.24
Assigned Pfam label(s) CL0126- CL0345- PF03945- CL0056- PF13963

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G2E099 4-119 YTVISEGGSGGNGFEMQSIKSIGLRSGKYVDQITINGVSHGENGGADRGTLTLEDGEYVTSIVVRSGSLIDYVEFNTNFNNQIKGGG…
A0A6A4DIC5 40-192 YAERASTLFGTTAGRPFTHDKVPPFGSISDVAVICGKKVDGISQVVKTHGHVSSEGILHGNPFGNREVFSLAKGEKLVTVEGFASHS…
A0A2E2SG73 261-417 None
A0A318YJP5 406-550 None
A0A559QVJ5 134-337 None
A0A2N9IFE7 9-250 None
A0A1Y2HC70 2-192 None
A0A1Y2HMM6 2-244 None
A0A820ALR9 1-124 None
A0A803PV63 275-439 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.