DPCstruct | MC33911

Metacluster Properties and Pfam Annotations

Number of structural domains718
Mean domain length (aa)160 ± 26 aa
Standard deviation of domain lengths25.94
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.47
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)14.43
Pfam Score96.24
Assigned Pfam label(s) CL0126- CL0345- PF03945- CL0056- PF13963

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2MTJ1 382-552 None
A0A6L5MRJ9 326-473 None
A0A0G4HJH1 55-221 None
A0A5N6W8G9 89-229 None
A0A7Y4MCJ0 938-1094 None
A0A413LB49 74-229 None
A0A7S2B0X7 67-206 None
A0A2G3CLE1 85-235 None
A0A803PUJ6 171-390 None
A0A1Q9CF87 393-552 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.