DPCstruct | MC28708

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)234 ± 30 aa
Standard deviation of domain lengths30.15
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.80
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R9L384 186-412 GPDEQLQGPGGGDSAGGTYQQLTLNLFLSETEQIQNIDEAENVKASSAFSFAQKDIDLVLRLGGNTDRLRERVTAAFEKQKPIPEIA…
A0A174HW10 1-209 MTKTGSILPEETLNAILRTGSNHNRTELRLIYNFMSVQTKEEYEEFVRNEYGNGGKGFIIDGKKYAVWFNKNGMQIALGETVRTKDK…
A0A373A6H5 6-179 None
A0A1M6T962 384-675 None
A0A7X3SIF0 1-254 None
A0A3D2Q120 2-207 None
A0A1Y4NIQ9 6-237 None
F9P9A5 4-213 None
F9P862 7-205 None
A0A396QFE4 4-261 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.