DPCstruct | MC28708

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)234 ± 30 aa
Standard deviation of domain lengths30.15
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.80
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3D5ICD5 1-235 None
A0A374EFD9 327-603 None
A0A2X1ZGC8 404-656 None
A0A2A6Z9M1 1-274 None
A0A373PC37 3-220 None
A0A4U9Y6H2 365-625 None
C0B645 1-243 None
D4K4Q2 351-604 None
A0A5M9HVJ7 5-206 None
A0A1Y4M2M6 2-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.