DPCstruct | MC2819

Metacluster Properties and Pfam Annotations

Number of structural domains3267
Mean domain length (aa)360 ± 72 aa
Standard deviation of domain lengths72.03
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score89.37
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)11.45
Pfam Score82.18
Assigned Pfam label(s) PF18951- PF00057- PF21307- PF11945- PF13968

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2VZK1 20-363 None
A0A6A3A2M0 169-506 None
A0A2E5EGF6 679-1005 None
A0A2H6IE82 44-322 None
A0A0G4GX53 209-666 None
A0A1Q7NM99 193-551 None
A0A1I1J4I3 724-1200 None
A0A3M7IUX5 28-423 None
A0A3P2A0R3 489-794 None
E8MGH9 342-807 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.