DPCstruct | MC2819

Metacluster Properties and Pfam Annotations

Number of structural domains3267
Mean domain length (aa)360 ± 72 aa
Standard deviation of domain lengths72.03
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score89.37
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.34
Mean intra-cluster sequence similarity (%)11.45
Pfam Score82.18
Assigned Pfam label(s) PF18951- PF00057- PF21307- PF11945- PF13968

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q5AR91 92-424 None
Q5B659 309-667 None
A0A5B0W914 39-328 None
A0A7W1HZ77 20-260 None
A0A3P6QW66 19-395 None
A0A0S7X5L1 3-320 None
A0A0S7X7V6 37-344 None
A0A017HPY5 2-345 None
A0A2E6TKI2 65-474 None
A0A135V1Y9 2-451 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.