DPCstruct | MC275

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)134 ± 26 aa
Standard deviation of domain lengths26.24
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score90.40
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)38.53
Pfam Score98.21
Assigned Pfam label(s) CL0003- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0K0DZB1 682-830 None
A0A1C3SMY3 378-538 None
A0A2A2K5I6 513-653 None
A0A437CBL7 46-143 None
A0A645DPB5 24-181 None
A0A4Y9JEQ6 13-149 None
A0A7X6YAY9 13-141 None
A0A349ZV58 883-1058 None
A0A7X8WG33 2-117 None
A0A0B2VP28 1029-1178 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.