DPCstruct | MC275

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)134 ± 26 aa
Standard deviation of domain lengths26.24
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score90.40
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)38.53
Pfam Score98.21
Assigned Pfam label(s) CL0003- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I7Q7F9 190-341 None
A0A818IIZ8 24-124 None
A0A379XJH9 2-110 None
A0A6A6MLM4 223-372 None
A0A1W9TCG7 40-205 None
A0A643C449 1017-1106 None
A0A7C1VW80 5-130 None
A0A7J0EKJ1 3-158 None
A0A7J7FCV8 448-596 None
A0A2K2DIK9 301-463 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.