DPCstruct | MC275

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)134 ± 26 aa
Standard deviation of domain lengths26.24
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score90.40
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)38.53
Pfam Score98.21
Assigned Pfam label(s) CL0003- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A834E6J9 331-479 KFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMREEDVEKLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLM…
A0A645H219 13-157 TLDGANVEIAEQVGDDNIYIFGMRVEKVNTLYQEGSYSPIGIYEQNAELRRALTQMIDGTLFPDNPALLQGLYHDLLFGSWGAPADP…
A0A0K6G366 91-237 None
A0A2G6JNW2 2-114 None
A0A6I9XT20 9-129 None
A0A817UP40 215-345 None
A0A0M3JM74 1-87 None
G9ZFE4 14-152 None
A0A2G9UX62 455-560 None
A0A1A9VZ66 67-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.