DPCstruct | MC2712

Metacluster Properties and Pfam Annotations

Number of structural domains500
Mean domain length (aa)101 ± 16 aa
Standard deviation of domain lengths15.87
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.02
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)35.78
Pfam Score98.90
Assigned Pfam label(s) PF03381- PF02161- PF02159- PF00104- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3EB83 104-219 None
A0A3Q7XPL9 107-230 None
A0A674D2K1 148-256 None
A0A0N4T826 29-122 None
A0A7R9LCA2 98-181 None
A0A1S3DLW3 7-130 None
A0A1S3DLS6 82-190 None
A0A016S9H1 33-140 None
A0A0R3PLQ9 4-91 None
A0A6P7GWL4 1-101 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.