DPCstruct | MC2712

Metacluster Properties and Pfam Annotations

Number of structural domains500
Mean domain length (aa)101 ± 16 aa
Standard deviation of domain lengths15.87
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.02
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)35.78
Pfam Score98.90
Assigned Pfam label(s) PF03381- PF02161- PF02159- PF00104- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3E891 1-92 None
H3E106 1-106 None
H3DY70 319-403 None
A0A4X3PD25 273-362 None
A0A2G9S816 3-96 None
E3MB68 2-75 None
E3M9A4 380-466 None
A0A182R0Q8 174-282 None
A0A814NDK9 30-151 None
E4XQU8 82-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.