DPCstruct | MC25899

Metacluster Properties and Pfam Annotations

Number of structural domains81
Mean domain length (aa)50 ± 8 aa
Standard deviation of domain lengths8.47
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.86
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)40.80
Pfam Score99.00
Assigned Pfam label(s) PF00057- PF02931

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E9IIB8 88-124 None
A0A1S3H9Q2 92-133 None
A0A8B6DA22 21-67 None
A0A016SBL8 34-76 None
A0A183CVD0 40-96 None
A0A3B5MUY4 18-74 None
A0A2H1CSM6 76-122 None
A0A4W5ND87 70-121 None
A0A4W5N9L4 1-56 None
A0A7J7EYV9 869-909 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.