DPCstruct | MC25899

Metacluster Properties and Pfam Annotations

Number of structural domains81
Mean domain length (aa)50 ± 8 aa
Standard deviation of domain lengths8.47
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.86
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)40.80
Pfam Score99.00
Assigned Pfam label(s) PF00057- PF02931

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4VGE6 195-232 GEQCPLGELRCLGGLCISLDQVCDGLAQCPDGADELNC
A0A182EZW2 1-50 MIFIECSEKRSVAENCGAKYYTCDSGDCIPREKACDRHYDCSDGSDEMKC
A0A1W0X5A3 363-415 None
A0A3B4G0Q4 32-82 None
A0A1B0BPK2 24-66 None
C3ZFD0 79-124 None
A0A7E4VIW5 132-196 None
A0A4Y2UT73 10-53 None
A0A1W0X9P2 611-649 None
A0A482WK41 120-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.