DPCstruct | MC24315

Metacluster Properties and Pfam Annotations

Number of structural domains291
Mean domain length (aa)78 ± 13 aa
Standard deviation of domain lengths12.53
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.20
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)31.26
Pfam Score93.99
Assigned Pfam label(s) PF00095- CL0220- PF09307- CL0620- CL0005

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
P84032 59-124 STKVKECGCYLKQKERKDSGRESAIIPQCEEDGKWAKKQLWEFNKSCWCVDEKGEQVGKIHHDCDS
A0A3Q3AA04 12-92 TGLNEPERPKTRCEHHRDSVQTTSPDGLPLLGAYVPQCDEHGQYQSQQCHGSTGYCWCVDSRGQERPGTRTSPGAPRADCS
C3ZZ07 6-102 None
A0A4P9D0M8 113-199 None
A0A2D4KHH5 32-126 None
A0A7E4W957 63-174 None
C3ZFN0 57-146 None
H3B8G7 195-276 None
A0A182TJ71 171-245 None
A0A7M5X4U3 673-754 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.