DPCstruct | MC24315

Metacluster Properties and Pfam Annotations

Number of structural domains291
Mean domain length (aa)78 ± 13 aa
Standard deviation of domain lengths12.53
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.20
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)31.26
Pfam Score93.99
Assigned Pfam label(s) PF00095- CL0220- PF09307- CL0620- CL0005

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7M5WQL0 355-426 None
A0A4Y2UN77 6-76 None
A0A820HNF6 9-82 None
A0A2C9JJD9 174-253 None
A0A3Q3FQD5 298-374 None
H3B1Y5 72-148 None
A0A6P8ICG6 110-189 None
A0A816RFA3 180-260 None
A0A0D8XPP1 4-76 None
A0A6P8RV95 100-216 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.