DPCstruct | MC22549

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)250 ± 45 aa
Standard deviation of domain lengths44.81
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)27.71
Pfam Score94.95
Assigned Pfam label(s) CL0540- PF03909- PF00183- PF15118- CL0207

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2L3S9 247-482 None
M1WW42 2-239 None
A0A2G2ZSK4 160-393 None
A0A401ZKN5 282-566 None
A0A812GRY6 577-852 None
C0NBV8 1181-1457 None
A0A3Q7GC15 58-235 None
A0A077MCN1 1-176 None
A0A251V8U0 15-299 None
A0A5B0RZ54 380-678 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.