DPCstruct | MC22549

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)250 ± 45 aa
Standard deviation of domain lengths44.81
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)27.71
Pfam Score94.95
Assigned Pfam label(s) CL0540- PF03909- PF00183- PF15118- CL0207

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A397VGB2 1-196 None
A0A7S3WW04 2-255 None
A0A7R9K8X7 92-338 None
A0A843V6N1 32-236 None
E1ZBE1 151-343 None
A0A7Y5JV26 3-190 None
A0A7R8ZPH4 287-574 None
A0A2I3SNK2 296-592 None
A0A0E0EU92 634-875 None
A0A3L6E6M8 116-401 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.