DPCstruct | MC22399

Metacluster Properties and Pfam Annotations

Number of structural domains259
Mean domain length (aa)225 ± 52 aa
Standard deviation of domain lengths52.17
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)17.68
Pfam Score83.88
Assigned Pfam label(s) PF21082- PF21088- CL0010- PF01544- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L8LV79 276-530 None
A0A1I0ILL8 36-274 None
A0A831JNH8 2-156 None
A0A5C6A6T1 18-240 None
A0A5D6Y2B4 95-343 None
D0MQJ6 2-223 None
A0A3D5YG42 7-149 None
A0A835PHN3 393-666 None
A0A378W2D6 3-156 None
A0A7S3BRX1 8-226 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.