DPCstruct | MC22399

Metacluster Properties and Pfam Annotations

Number of structural domains259
Mean domain length (aa)225 ± 52 aa
Standard deviation of domain lengths52.17
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)17.68
Pfam Score83.88
Assigned Pfam label(s) PF21082- PF21088- CL0010- PF01544- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D8FBG1 52-208 PSRTGDWVLLADGTYGNVTAQTPEIVTLRLKGGALKYYPTSDYMAQSPTNLSHGYRLTCIFGVDYQHQGIVIREIQEMMKKAVSEGL…
A0A2V7EWQ7 24-264 VLGTLVAAAGERRALGVGVTGLARAAVRVFVLVIGGLILLDAIGVRITPLLTALGVGGLAVALALQDTLSNLFAGVHLLADRPIRVG…
A0A0N0P9C9 10-161 None
A0A4Y7KRK2 71-289 None
A0A4Y7JDF5 65-279 None
A0A7V9ZZG1 1-185 None
A0A7V6GNP8 606-778 None
A0A1B0C786 183-414 None
A0A1S8VLH2 950-1196 None
A0A7J3WB96 13-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.