DPCstruct | MC22399

Metacluster Properties and Pfam Annotations

Number of structural domains259
Mean domain length (aa)225 ± 52 aa
Standard deviation of domain lengths52.17
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)17.68
Pfam Score83.88
Assigned Pfam label(s) PF21082- PF21088- CL0010- PF01544- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A651DSB7 136-381 None
F2UME1 87-335 None
A0A350EZH4 42-287 None
A0A504U7Y1 149-425 None
Q8IIS3 1139-1392 None
A0A812IKM5 324-609 None
A0A1I2SD95 134-418 None
A0A835YNP7 33-271 None
A0A497QUH9 41-314 None
A0A645EFL8 2-214 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.