DPCstruct | MC22399

Metacluster Properties and Pfam Annotations

Number of structural domains259
Mean domain length (aa)225 ± 52 aa
Standard deviation of domain lengths52.17
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.03
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)17.68
Pfam Score83.88
Assigned Pfam label(s) PF21082- PF21088- CL0010- PF01544- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z6LX46 22-245 None
R0KKQ0 4-133 None
A0A6M1SJY6 8-188 None
A0A845X0Q2 462-722 None
A0A484N2H3 20-245 None
A0A0W1KKG3 14-205 None
A0A3D2INE3 742-990 None
A0A448YY74 73-339 None
A0A7K4EZ59 7-144 None
A0A0K9RVT2 531-724 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.