DPCstruct | MC22398

Metacluster Properties and Pfam Annotations

Number of structural domains1150
Mean domain length (aa)126 ± 25 aa
Standard deviation of domain lengths24.69
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.62
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.11
Pfam Score92.77
Assigned Pfam label(s) CL0084- PF07335- CL0029- CL0229- CL0209

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A4Z1N6 50-188 None
A4YU52 193-320 None
A0A177WIL8 12-141 None
A0A0K9QQ09 295-436 None
A0A318B1A9 2-96 None
J5TUL5 20-137 None
J5TEI0 1-203 None
A0A818ZF54 20-105 None
A0A416PCI9 233-329 None
A0A6J5VD55 1-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.